​Lenalidomide in follicular lymphoma

2021-02-23 Blood中文時訊

BLOOD SPOTLIGHT| JUNE 11, 2020

Lenalidomide in follicular lymphoma

Christopher R. Flowers, John P. Leonard, Nathan H. Fowler

Blood (2020) 135 (24): 2133–2136.

https://doi.org/10.1182/blood.2019001751

Abstract

Lenalidomide is an immunomodulatory drug approved in the United States for use with rituximab in patients with relapsed/refractory follicular lymphoma. We reviewed data from trials addressing the safety and efficacy of lenalidomide alone and in combination with rituximab as a first-line therapy and as a treatment of patients with relapsed/refractory follicular lymphoma. Lenalidomide-rituximab has been demonstrated to be an effective chemotherapy-free therapy that improves upon single-agent rituximab and may become an alternative to chemoimmunotherapy.

Subjects:

Blood Spotlight, Clinical Trials and Observations, Lymphoid Neoplasia

Topics:

follicular lymphoma, lenalidomide, rituximab

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