A 28-year-old woman with headache, dizziness, and seizure
A
B
C
What is your diagnosis?
The answer is Neurocutaneous Melanosis
Neurocutaneous melanosis is a congenital phakomatosis characterized by giant or multiple cutaneous melanocytic nervi as well as benign and malignant melanotic lesions of CNS.
This is such a case with malignant melanoma (hyperintense on T1WI, mixed SI on T2WI, and avid contrast enhancement) plus leptomeningeal melanomas; appeared as a hyperintense focus in left ooccpital sulcus on T1WI (A, arrow) and diffuse leptomenigneal contrast enhancement(B).
中文版：
女性，28歲，頭痛、頭暈、癲癇發作
診斷：神經皮膚黑變病
神經皮膚黑變病是一種斑痣性錯構瘤病，其特徵為皮膚神經大片或多發黑色素痣，同時合併中樞神經系統良性和惡性黑色素沉著病。
本病例合併神經系統黑色素瘤（T1WI高信號，T2WI呈混雜信號，增強後明顯強化）和軟腦膜黑色素瘤；T1WI表現為左側枕葉腦溝內局灶性高信號（A圖箭頭）以及瀰漫性軟腦膜強化（B）。
From AJNR Classic Case