基於網際網路的前庭康復可有效治療50歲及以上成人慢性前庭症候群
作者:
小柯機器人發布時間:2019/11/7 16:58:50
荷蘭阿姆斯特丹大學Vincent A van Vugt團隊在研究中取得進展。他們發現,網際網路為基礎的前庭康復伴或不伴物理治療支持可用於治療50歲及以上的成人慢性前庭症候群。相關論文11月5日在線發表於《英國醫學期刊》。
在這項實用、三臂、平行組、個體隨機對照試驗中,研究組招募了322名50歲及以上患有慢性前庭症候群的成年人。將其隨機分為三組,其中單獨前庭康復(VR)組包括為期6周的網際網路幹預,每周在線學習課程,並進行日常鍛鍊,每日10-20分鐘。混合VR組在基於單獨VR組的基礎上,增加面對面的物理治療支持,醫生在第1周和第3周上門治療。普通護理組則接受全科醫生的標準護理,無任何限制。
在意向治療分析中,單獨VR組和混合VR組的參與者在治療6個月後的眩暈症狀量表(VSS-SF)得分顯著低於普通護理組,隨訪3個月後該評分差異依舊存在。在治療3個月和6個月時,與普通護理組相比,單獨和混合VR組更少發生頭暈相關損害和焦慮症,且主觀前庭症狀顯著改善。試驗期間未發生與在線VR相關的嚴重不良事件。
總之,單獨和混合VR是治療50歲及以上成人慢性前庭症候群的安全有效的方法,在線VR較易獲得,可改善治療不足患者的療效。
附:英文原文
Title: Internet based vestibular rehabilitation with and without physiotherapy support for adults aged 50 and older with a chronic vestibular syndrome in general practice: three armed randomised controlled trial
Author: Vincent A van Vugt, Johannes C van der Wouden, Rosie Essery, Lucy Yardley, Jos W R Twisk, Henritte E van der Horst, Otto R Maarsingh
Issue&Volume: 2019/11/05
Abstract:
Objective To investigate the clinical effectiveness and safety of stand alone and blended internet based vestibular rehabilitation (VR) in the management of chronic vestibular syndromes in general practice.
Design Pragmatic, three armed, parallel group, individually randomised controlled trial.
Setting 59 general practices in the Netherlands.
Participants 322 adults aged 50 and older with a chronic vestibular syndrome.
Interventions Stand alone VR comprising a six week, internet based intervention with weekly online sessions and daily exercises (10-20 minutes a day). In the blended VR group, the same internet based intervention was supplemented by face-to-face physiotherapy support (home visits in weeks 1 and 3). Participants in the usual care group received standard care from a general practitioner, without any restrictions.
Main outcome measures The primary outcome was vestibular symptoms after six months as measured by the vertigo symptom scale-short form (VSS-SF range 0-60, clinically relevant difference ≥3 points). Secondary outcomes were dizziness related impairment, anxiety, depressive symptoms, subjective improvement of vestibular symptoms after three and six months, and adverse events.
Results In the intention-to-treat analysis, participants in the stand alone and blended VR groups had lower VSS-SF scores at six months than participants in the usual care group (adjusted mean difference −4.1 points, 95% confidence interval −5.8 to −2.5; and −3.5 points, −5.1 to −1.9, respectively). Similar differences in VSS-SF scores were seen at three months follow-up. Participants in the stand alone and blended VR groups also experienced less dizziness related impairment, less anxiety, and more subjective improvement of vestibular symptoms at three and six months. No serious adverse events related to online VR occurred during the trial.
Conclusion Stand alone and blended internet based VR are clinically effective and safe interventions to treat adults aged 50 and older with a chronic vestibular syndrome. Online VR is an easily accessible form of treatment, with the potential to improve care for an undertreated group of patients in general practice.
DOI: 10.1136/bmj.l5922
Source: https://www.bmj.com/content/367/bmj.l5922