2020年12月18日，據歐盟食品安全局（EFSA）消息，應歐盟委員會要求，歐盟動物飼料添加劑和產品（FEEDAP）研究小組就大腸桿菌CGMCC 13325生產的L-蘇氨酸（L‐threonine）作為所有動物飼料添加劑的安全性和有效性發表科學意見。
經過評估，專家小組認為該添加劑對消費者和環境是安全的。在缺乏數據的情況下，專家小組無法就該添加劑作為皮膚、眼睛刺激物或皮膚敏化劑的可能性得出結論。評估中的添加劑被認為是非反芻動物物種胺基酸L-蘇氨酸的有效來源。為了使補充的L-蘇氨酸對反芻動物和非反芻動物同樣有效，需要防止其在瘤胃中降解。部分原文報導如下：
Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on l‐threonine produced by fermentation when used as a nutritional additive in feed and water for drinking for all animal species and categories. The product under assessment is l‐threonine produced using a genetically modified strain of E. coliCGMCC 13325. The Panel notes that three out of five batches of the additive do not comply with the minimum specification of 98.5% l‐threonine on a dry matter basis proposed by the applicant. The production strain and its DNA were not detected in the final additive. Therefore, the final product does not give raise to any safety concern regarding the genetic modification of the production strain. The use of l‐threonine produced using E. coliCGMCC 13325 in supplementing feed to compensate for threonine deficiency in feedingstuffs is safe for the target species. The FEEDAP Panel identified risks of nutritional imbalances and hygienic concerns for amino acids when administered simultaneously in feed and in water for drinking. The use of l‐threonine produced by fermentation using E. coliCGMCC 13325 in animal nutrition is considered safe for the consumers and for the environment. There is a risk from the inhalation exposure to endotoxins for persons handling the additive. In the absence of data, the FEEDAP Panel cannot conclude on the potential of l‐threonine produced using E. coliCGMCC 13325 to be a skin or eye irritant or a skin sensitiser. The additive under assessment is regarded as an effective source of the amino acid l‐threonine for all non‐ruminant species. For the supplemental l‐threonine to be as efficacious in ruminants as in non‐ruminant species, it requires protection against degradation in the rumen.
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