Your support will certainly make a difference in my cause.
你的支持肯定對我的事業很有影響。
【核心詞彙】make a difference
make a / the difference: to have an important effect or influence on something or someone 有作用，有影響
If something makes a differenceor makes a lot of difference, it affects you and helps you in what you are doing. If something makes no difference, it does not have any effect on what you are doing. 有 (某程度的) 影響/毫無影響
【例句拓展】
1. The Act will make no differenceto my business.
這個法案對我的生意不會有什麼影響。
2. I don'tthink it will make a lot of difference what color it is.
我認為顏色無關緊要。( make no difference)
3. Where you live can make such a difference tothe way you feel.
你居住的位置會對你的感覺產生很大的影響。
4. Whatever she did, it made no difference.
不管她做什麼都沒有用。
5. I can make a differencein this world.
世界會因我而不同。
6. Your absence make a quite difference to me.
你的缺席對我產生重大影響。