2018年度OncLive頒獎儀式圓滿落幕。
剛剛OncLive年度頒獎儀式在芝加哥的阿德勒天文館圓滿落下帷幕。今年21位變革者獲得了『癌症關愛巨人』大獎。自該獎2013年創立以來，這是獲獎人數最多的一次。他們是變革的催化劑，富有遠見卓識、勇於創新並取得了矚目的成就，心中肩負著極強的使命感。
今年，大獎的被提名人數創了歷史記錄。由於在患者關愛、臨床實踐和轉化研究上的開創、突破性的貢獻，這些傑出的醫生和研究者促使領域變革的發生。此外，今年美國以外的提名人也是最多的一次（將近24名）。
由Patrick I. Borgen (MD, chairman of the Department of Surgery and director of the Maimonides Breast Program at Maimonides Medical Center in Brooklyn, New York) 領銜的顧問委員會審閱了被提名人的職業成就，然後遴選出了171位晉級者。之後由知名的腫瘤學家和血液學家組成的專家評選委員會對這些人員進行投票。候選人遍布所有疾病領域，很多人都取得了矚目的成就。
獲獎者劃分為21個業務和研究類別：
乳腺癌
癌症診斷
中樞神經系統惡性腫瘤
社區聯繫、教育和癌症政策
藥物開發
胃腸癌
泌尿生殖器癌
婦科腫瘤
頭頸癌
腫瘤免疫（含細胞治療）
白血病
肺癌
淋巴瘤
黑色素瘤和皮膚癌症
多發性骨髓瘤
兒科腫瘤學
預防和遺傳學
放射腫瘤學
支持療法、保守療法和老年病學
腫瘤外科
轉化科學發展
顧問委員會Borgen先生說到：「我們非常自豪能為『癌症關愛巨人』遴選出這些傑出人士。他們的犧牲、奮鬥、勝利和失敗應該被未來一代的人們所銘記。正因為他們取得的成就，這些人才不會眼睜睜的看著至愛的人遭受癌症帶來的痛苦或死亡。」
『癌症關愛巨人』獎旨在表彰在癌症研究和患者治療方面取得卓越成就的個人。獎項對獲得者的個人要求極高，必須滿足如下要求：無私忘我，對患者抱有關愛之心，心懷對理解癌症和開發出革命性的癌症治療方法的渴望。
華人科學家陳列平教授獲得了腫瘤免疫領域的『Giants of Cancer Care』(癌症關愛巨人) 稱號，以表彰其在發現PD-1/PD-L1通路及相關免疫抑制功能上所取得的成就。
陳列平教授所獲獎盃
其他獲獎者如下：
George W. Sledge, Jr, MD, Stanford University – Breast Cancer
Laura J. Esserman, MD, MBA, University of California San Francisco/Helen Diller Family Comprehensive Cancer Center – Cancer Diagnostics
W.K. Alfred Yung, MD, The University of Texas MD Anderson Cancer Center – CNS Malignancies
Richard L. Schilsky, MD, ASCO – Community Outreach/Education/Cancer Policy
Joseph R. Bertino, MD, Rutgers Cancer Institute of New Jersey – Drug Development
Josep Tabernero, MD, PhD, Vall d』Hebron Institute of Oncology – Gastrointestinal Cancer
Nicholas J. Vogelzang, MD, Comprehensive Cancer Centers of Nevada – Genitourinary Cancers
Maurie Markman, MD, Cancer Treatment Centers of America – Gynecologic Cancers
Waun Ki Hong, MD, The University of Texas MD Anderson Cancer Center – Head and Neck Cancers
Lieping Chen, MD, PhD, Yale University – Immuno-Oncology
Michael J. Keating, MD, The University of Texas MD Anderson Cancer Center – Leukemia
Bruce E. Johnson, MD, Dana – Farber Cancer Institute/Harvard Medical School – Lung Cancer
James O. Armitage, MD, University of Nebraska – Lymphoma
Caroline Robert, MD, PhD, Institute Gustave Roussy, Paris, France – Melanoma and Skin Cancers
Bart Barlogie, MD – Mount Sinai – Myeloma
Michael P. Link, MD, Stanford University – Pediatric Oncology
Judy E. Garber, MD, MPH, Dana – Farber Cancer Institute –Prevention/Genetics
Eli J. Glatstein, MD, University of Pennsylvania School of Medicine – Penn Medicine – Radiation Oncology
Patricia A. Ganz, MD, David Geffen School of Medicine and Jonsson Comprehensive Cancer Center – Supportive Care/Palliative/Geriatric
Armando Giuliano, MD, Cedars – Sinai Medical Center (Los Angeles) – Surgical Oncology
V. Craig Jordan, OBE, PhD, DSc, FMedSci, The University of Texas MD Anderson Cancer Center – Translational Scientific Advancements
當晚，阿德勒天文館群星璀珊，星光閃耀。現場集錦如下：
左圖：陳列平博士發表獲獎感言；右圖：陳列平博士與嘉賓合影
陳列平博士與其他嘉賓合影，從左至右：左一為Tom Lynch, 腫瘤內科醫生，現任百時美施貴寶公司(Bristol-Myer Squibb) EVP & CSO，前」巨人」獎獲得者，原耶魯癌症中心主任 ；左二為耶魯綜合癌症中心助理主任Anees B. Chagpar；左三為耶魯大學 UTC 癌症研究教授，免疫學、醫學（腫瘤學）和皮膚病學教授，耶魯癌症中心免疫學部聯合主任陳列平；左四為Roy Herbst醫生，現耶魯腫瘤內科主任，癌症中心副主任。
不久前的4月9日，在CST創新轉化中心承辦的首屆全球華人科學家創新轉化30人高峰論壇上，陳列平教授榮膺『全球華人科學家-CST卓越創新轉化獎』(點擊連結可以了解更多獎項詳情)。
「全球華人科學家-CST卓越創新轉化獎」 是CST 2018 年新設的一項獎項，用以獎勵在研究人類生命進程各重大疾病的基礎機制中有突破發現並積極推動向臨床應用轉化的華人科學家們。
自1990年代初至今，陳列平教授一直致力於免疫細胞共刺激、共抑制機理及腫瘤免疫治療和免疫疾病治療的相關研究。1992年，陳列平教授開拓性地發表了概念驗證性研究的第一個證據，通過向腫瘤細胞引入B7-1，可增強腫瘤免疫，表明操縱B7-CD28／CTLA-4分子家族可用於腫瘤的免疫治療。這項研究激發了針對這一途徑治療人類癌症的後續研究。此項成果啟發了使用靶向CTLA-4抗體 [B7-CD28家族的一個分子] 治療癌症的一系列後續研究，由此開創了腫瘤治療的全新理念。
陳列平教授的研究奠定了抗PD-1及PD-L1進行癌症治療在基礎研究與轉化研究的理論基礎。在基礎研究中，他的實驗室共同發現了PD-1/PD-L1通路並闡明其功能。這些發現包括發現B7-H1（PD-L1）分子；它的免疫抑制功能以及正常的生理功能。在轉化研究中，他的研究確立了將PD-1/PD-L1通路作為癌症免疫治療的目標。
以往歷屆獲獎者:
2017年：
Norman Wolmark, MD, National Surgical Adjuvant Breast and Bowel Project (NSABP) / NRG Oncology – BREAST CANCER
Charles S. Fuchs, MD, MPH, Yale Cancer Center/Smilow Cancer Hospital – GASTROINTESTINAL CANCER
Daniel P. Petrylak, MD, Yale University School of Medicine – GENITOURINARY CANCER
Kanti R. Rai, MD, North Shore University Hospital – LIJ/ The Feinstein Institute for Medical Research – HEMATOLOGIC MALIGNANCIES
Thomas F. Gajewski, MD, PhD, University of Chicago Medicine – IMMUNO-ONCOLOGY INCLUDING CELL-BASED THERAPIES
David R. Gandara, MD, University of California, Davis – LUNG CANCER
John M. Kirkwood, MD, University of Pittsburgh School of Medicine – MELANOMA
Joseph V. Simone, MD, (retired) Huntsman Cancer Institute – PEDIATRIC ONCOLOGY
Herman D. Suit, MD, MSc, PhD, Harvard Medical School/Massachusetts General Hospital – RADIATION ONCOLOGY
Lewis C. Cantley, PhD, Sandra and Edward Meyer Cancer Center at Weill Cornell Medical College – SCIENTIFIC ADVANCES/ DRUG DEVELOPMENT
Hyman B. Muss, MD, University of North Carolina Lineberger Cancer Center – SUPPORTIVE/PALLIATIVE/ GERIATRIC CARE
John L. Cameron, MD, Johns Hopkins University School of Medicine – SURGICAL ONCOLOGY
2016年：
Larry Norton, MD, Memorial Sloan Kettering Cancer Center – BREAST CANCER
Joyce A. O』Shaughnessy, MD, US Oncology/Texas Oncology/Baylor Charles A. Sammons Cancer Center – COMMUNITY OUTREACH/EDUCATION
Daniel D. Von Hoff, MD, Translational Genomics Research Institute (TGEN) – GASTROINTESTINAL CANCER
Robert J. Motzer, MD, Memorial Sloan Kettering Cancer Center – GENITOURINARY CANCER
James F. Holland, MD, Icahn School of Medicine at Mount Sinai – HEMATOLOGIC MALIGNANCIES
Frances A. Shepherd, MD, Princess Margaret Hospital – LUNG CANCER
Jeffrey S. Weber, MD, PhD, NYU Langone Medical Center – MELANOMA
Samuel Hellman, MD, University of Chicago (Retired) – RADIATION ONCOLOGY
John Mendelsohn, MD, The University of Texas MD Anderson Cancer Center – SCIENTIFIC ADVANCES
Sir Murray F. Brennan, MD, Memorial Sloan Kettering Cancer Center – SURGICAL ONCOLOGY
2015年：
Gabriel N. Hortobagyi, MD, The University of Texas MD Anderson Cancer Center – BREAST CANCER
Harold P. Freeman, MD, Founder, Harold P. Freeman Patient Navigation Institute – COMMUNITY OUTREACH/EDUCATION
Robert J. Mayer, MD, Dana-Farber Cancer Institute – GASTROINTESTINAL CANCER
Maha H. Hussain, MB ChB，University of Michigan Comprehensive Cancer Center – GENITOURINARY CANCER
Robert C. Bast Jr, MD，The University of Texas MD Anderson Cancer Center – GYNECOLOGIC MALIGNANCIES
Carl H. June, MD, Perelman School of Medicine at the University of Pennsylvania – IMMUNO-ONCOLOGY
John Minna, MD, University of Texas Southwestern Medical Center – LUNG CANCER
Emil J. Freireich, MD, DSc, The University of Texas MD Anderson Cancer Center – LYMPHOID NEOPLASMS
Antoni Ribas, MD, PhD, UCLA School of Medicine/Jonsson Comprehensive Cancer Center – MELANOMA
Clara D. Bloomfield, MD, The Ohio State University Comprehensive Cancer Center – MYELOID NEOPLASMS
Robert A. Weinberg, PhD, Massachusetts Institute of Technology/Whitehead Institute – SCIENTIFIC ADVANCES
Charles L. Loprinzi, MD, Mayo Clinic – SUPPORTIVE/PALLIATIVE CARE
2014年：
Dennis J. Slamon, MD, PhD, UCLA Jonsson Comprehensive Cancer Center – Breast Cancer
Howard A. Burris III, MD, Sarah Cannon Research Institute – Drug Development
John R. Seffrin, PhD, American Cancer Society – Education
George D. Demetri, MD, Dana-Farber Cancer Institute/Harvard Cancer Center – Gastrointestinal Cancer
Janet Davison Rowley, MD (deceased 2013), University of Chicago – Genetics
Philip W. Kantoff, MD, Dana-Farber Cancer Institute/Harvard Cancer Center – Genitourinary Cancer
Kie Kian Ang, MD, PhD (deceased 2013), The University of Texas MD Anderson Cancer Center – Head & Neck Cancer
Hagop M. Kantarjian, MD, A world leader in leukemia treatment – Leukemia
Paul A. Bunn Jr, MD, University of Colorado Cancer Center – Lung Cancer
Riccardo Dalla-Favera, MD, Columbia University Medical Center – Lymphoma
Jedd D. Wolchok, MD, PhD, Memorial Sloan Kettering Cancer Center – Melanoma
Kenneth C. Anderson, MD, Dana-Farber Cancer Institute/Harvard Cancer Center – Myeloma
Edith A. Perez, MD, Mayo Clinic – Outreach
Patrick C. Walsh, MD, Johns Hopkins University – Prostate Cancer
James P. Allison, PhD, The University of Texas MD Anderson Cancer Center – Scientific Advances
Jimmie C. Holland, MD, Memorial Sloan Kettering Cancer Center – Supportive Care
2013年：
Bernard Fisher, MD, University of Pittsburgh – Breast Cancer
Bert Vogelstein, MD, Johns Hopkins Medicine – Gastrointestinal Cancer
Elizabeth H. Blackburn, PhD, University of California, San Francisco – Genetics
Lawrence H. Einhorn, MD, Indiana University – Genitourinary Cancer
Everett E. Vokes, MD, University of Chicago – Head & Neck Cancer
Brian J. Druker, MD, Oregon Health & Science University – Leukemia
Thomas J. Lynch, Jr, MD, Yale Cancer Center – Lung Cancer
Vincent T. DeVita, Jr, MD, Yale Cancer Center – Lymphoma
Steven A. Rosenberg, MD, PhD, National Cancer Institute – Melanoma
Robert A. Kyle, MD, Mayo Clinic – Myeloma
Charles L. Sawyers, MD, Memorial Sloan-Kettering Cancer Center – Prostate Cancer
Moses Judah Folkman, MD (1933-2008), Harvard Medical School – Scientific Advances
關於Giants of Cancer Care：
該獎項頒發給全球在癌症領域做出卓越貢獻的頂尖研究者和教育者。由領域內著名的腫瘤學家通過嚴格的遴選，重點考察候選人的臨床影響，貢獻的意義及最終的成就這幾個方面，從而選出相應的獲獎人。
本文照片由陳列平教授提供
本文部分內容翻譯和內容源自網址：https://www.onclive.com/publications/oncology-live/2018/vol-19-no-11/onclive-salutes-21-visionaries?from=singlemessage&isappinstalled=0