【讀心有術】739期:預後的價值有哪些?從QRS波終末現象說起(3)

【讀心有術】737期：預後的價值有哪些？從QRS波終末現象說起（1）

【讀心有術】738期：預後的價值有哪些？從QRS波終末現象說起（2）

Two of the studies did not consider the Haïssaguerre/ J-wave pattern but only reported ST elevation and should not be included. Six studies remain, but one had all-cause mortality as an end point, was really a case-control rather than a prospective study, and only reported a weak hazard ratio (1.5), leaving 5 studies for tabulation. Four of these 5 considered the Haïssaguerre pattern and found a hazard for CV and/ or arrhythmic death. In tabulating the results of these studies, the impact of positive publication bias must be considered: authors and editors favor positive, exciting results over negativity. While shortcomings of these studies have been pointed out above, the majority favor a weak association of CV risk with the Haïssaguerre pattern. The average hazard ratio of approximately 3 is meaningful for a risk factor that can be modified (i.e., HBP, cigarette smoking), but does not provide adequate power for clinical decision-making, particularly when the risk may require 10 to 15 years before it manifests.