隨著社會經濟快速發展，人們的生活水平不斷提高，膳食結構改變以及人口老齡化進程的加速，全球範圍內，慢性基礎病患者（如高血壓、糖尿病、骨質疏鬆、動脈粥樣硬化、腫瘤等）不斷增加，嚴重降低人們的生活質量和影響壽命，已逐漸轉變成為國家最主要公共衛生問題。因此，如何預防慢性基礎病發生和發展，加強對其發病機制和預防措施的研究，不僅是現代營養學研究面臨的挑戰，也是保護人們健康和促進社會發展的重要課題，具有重要的現實意義。
天然營養素是維持人類生命必不可少的物質，此類物質不但容易獲取，沒有明顯副作用，而且被越來越多的研究證實能發揮預防和治療慢性疾病的功效。
為了更好的研究和挖掘更多的具有預防和治療各類慢性病的天然營養素，近日，南方醫科大學廖文鎮副教授、中山大學百人計劃專家袁苗苗副教授、湘潭大學曹毅副教授、美國邁阿密大學Xian Wu助理教授和義大利博洛尼亞大學Silvia Turroni副教授等聯合在SCI期刊Frontiers in Bioengineering and Biotechnology（JCR Q1，影響因子5.122）中主辦題為「Novel Biological Synthesis of Nutrients for Chronic Diseases Intervention」的專刊，希望籍此為世界範圍內專注於營養與慢性病幹預領域的研究者提供廣泛深入交流的平臺，歡迎各位同仁不吝賜稿！
It is well known that chronic diseases, including hypertension, diabetes mellitus, osteoporosis, atherosclerosis, cancer and so forth, are the major public health issues decreasing life quality and expectancy in the past decades. In that context, the continuous administration of various medicines is required to reduce the morbidity and mortality of patients suffering from those chronic diseases. Unfortunately, many chemically synthesized medical compounds have been reported with serious and inevitable side effects, increasing the risk of other diseases, and reducing tolerance and compliance of patients. Nutrients, the building blocks of life, have shred brand-new light on the prevention and treatment of chronic diseases. Nutrients originating from natural plants, such as daidzein from soybean and nobiletin from mandarin orange, have been widely studied for their preventive and therapeutic effect against chronic diseases. Compared to chemically synthesized medicines, nutrients show fewer side effects, which conferred their better acceptance by patients. Besides, the application of biocompatible materials, such as different kinds of hydrogels and novel nanomaterials, can enlarge the efficacies of those nutritional intervention against chronic diseases. Therefore, the strategies aforementioned are worth being studied and revealed in-depth for the prevention and treatment of chronic diseases as promising complements to the traditional therapeutical strategies.
Novel synthetic pathways for nutrient production in plants, with potential clinical applications.
The influence of nutrition on metabolites synthesized by the intestinal microbiota system in patients with chronic diseases.
Novel methods to combine various nutrients to synthesize a beneficial brand-new material.
Functional oligomers (such as oligosaccharides, peptides, etc.) produced through biosynthetic methods and the molecular mechanisms with biomedical applications in the case of chronic diseases.
Abstract 03 August 2020
Manuscript 01 December 2020
投稿連結：https://www.frontiersin.org/research-topics/14573/novel-biological-synthesis-of-nutrients-for-chronic-diseases-intervention
(點擊閱讀原文可跳轉)
Frontiers in Bioengineering and Biotechnology希望通過彌合基礎科學發現與臨床應用之間經常存在的鴻溝，促進兩者的交流與融合。本專刊歡迎生物工程發展和生物技術開發的前沿性研究的投稿。Name: Wenzhen Liao
Position: Lead Editor
Primary research areas:
Structure-activity relationship of nutrient active substances, prevention and treatment of chronic diseases.
E-mail: wenzhenliao@smu.edu.cn
Name: Yi Cao
Position: Editor
Primary research areas:
Nanotoxicology and nanomedicine, with a focus on inorganic nanomaterials.
E-mail: caoyi39@xtu.edu.cn
Name: Miaomiao Yuan
Position: Editor
Primary research areas:
Nanomaterials for Cancer Diagnosis and Therapy,
Research on Antitumor Natural Products.
E-mail: yuanmm3@mail.sysu.edu.cn
Name: Xian Wu
Position: Editor
Primary research areas:
Dietary Strategies of Obesity prevention, Chronic Inflammation-associated diseases.
E-mail: wux57@MiamiOH.edu
Name: Silvia Turroni
Position: Editor
Primary research areas:
Chemistry and Biotechnology of Fermentation.
E-mail: silvia.turroni@unibo.it
歡迎廣大科研人員的關注和投稿!