雜誌
IF
英文題目
中文題目
The New England journal of medicine
75
Purifying Selection against Pathogenic Mitochondrial DNA in Human T Cells
人T細胞致病性線粒體DNA的純化篩選
Nature
43
A single-cell transcriptome atlas of marsupial embryogenesis and X inactivation
有袋類動物胚胎發生與X失活的單細胞轉錄組圖譜
Nature
43
Epigenetic regulator function through mouse gastrulation
小鼠原腸胚形成的表觀遺傳調節功能
Nature
43
Heterotypic cell-cell communication regulates glandular stem cell multipotency
異質性的細胞間通訊調節腺幹細胞多能性
Science (New York, N.Y.)
42
Designed protein logic to target cells with precise combinations of surface antigens
蛋白質設計算法可實現精準靶向細胞表面抗原
Science (New York, N.Y.)
42
Mosquito cellular immunity at single-cell resolution
單細胞分辨下的蚊子細胞免疫
Cell
39
CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling
CD81通過FAK信號調控米色脂肪祖細胞的生長和能量平衡
Cell
39
Elevated Calprotectin and Abnormal Myeloid Cell Subsets Discriminate Severe from Mild COVID-19
鈣保護蛋白升高和骨髓細胞亞群異常可區分重度和輕度COVID-19
Cell
39
Finding a Needle in a Haystack: Identification of a Beige Fat Progenitor
大海撈針：一種米色脂肪祖細胞的鑑定
Cell
39
Memory Sequencing Reveals Heritable Single-Cell Gene Expression Programs Associated with Distinct Cellular Behaviors
記憶測序揭示了與不同細胞行為相關的可遺傳單細胞基因表達程序
Cell
39
Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition
小膠質細胞需要CD4 T細胞來完成胎兒到成人的過渡
Cell
39
Molecular Pathways of Colon Inflammation Induced by Cancer Immunotherapy
腫瘤免疫治療誘導結腸炎症的分子途徑
Cell
39
Self-Reporting Transposons Enable Simultaneous?Readout of Gene Expression and Transcription?Factor Binding in Single Cells
自反饋轉座子可在單個細胞中同時讀取基因表達和轉錄因子結合
Cell
39
Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment
嚴重的COVID-19表現為一個失調的髓樣細胞室
Cell
39
CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling
CD81通過FAK信號通路調控米色脂肪祖細胞的生長及能量平衡
Cell
39
Coupled scRNA-Seq and Intracellular Protein Activity Reveal an Immunosuppressive Role of TREM2 in Cancer
聯合單細胞RNA測序及胞內蛋白活性分析揭示TREM2在癌症中的免疫抑制作用
Nature biotechnology
37
A singular view of COVID-19
COVID-19的奇觀
Nature biotechnology
37
Generalizing RNA velocity to transient cell states through dynamical modeling
通過動力學模型將RNA速度推廣到瞬時細胞狀態
Nature biotechnology
37
Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling
大規模平行單細胞線粒體DNA基因分型和染色質分析
Nature biotechnology
37
Sci-fate characterizes the dynamics of gene expression in single cells
Sci命運表徵單個細胞中基因表達的動態
Nature biotechnology
37
Single-cell metabolic profiling of human cytotoxic T cells
人細胞毒性T細胞的單細胞代謝譜研究
Nature medicine
36
A single-cell landscape of high-grade serous ovarian cancer
高級別漿液性卵巢癌的單細胞圖像
Nature medicine
36
Author Correction: A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors
作者更正：用於新鮮和冷凍人體腫瘤的單細胞和單核RNA序列工具箱
Nature medicine
36
Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis
不同的滑膜組織巨噬細胞亞群調節和緩解類風溼關節炎的炎症
Nature medicine
36
Single-cell atlas of colonic CD8(+) T cells in ulcerative colitis
潰瘍性結腸炎中結腸CD8（+）T細胞單細胞圖譜
Nature reviews. Genetics
33
Integrating genetic and non-genetic determinants of cancer evolution by single-cell multi-omics
利用單細胞多組學整合癌症進化的遺傳和非遺傳決定因素
Nature methods
31
Cumulus provides cloud-based data analysis for large-scale single-cell and single-nucleus RNA-seq
積云為大規模單細胞和單核RNA序列提供了基於雲的數據分析
Nature genetics
28
Imprecise DNMT1 activity coupled with neighbor-guided correction enables robust yet flexible epigenetic inheritance
不精確的DNMT1活性與鄰居引導的校正相結合，可以實現穩健而靈活的表觀遺傳
Nature genetics
28
Recurrent inversion toggling and great ape genome evolution
反覆倒位切換與類人猿基因組進化
Nature genetics
28
Single-cell transcriptomics identifies a distinct luminal progenitor cell type in distal prostate invagination tips
單細胞轉錄組鑑定前列腺遠端凹陷尖端的一種獨特的腔前體細胞類型
Cancer cell
27
Emergence of a High-Plasticity Cell State during Lung Cancer Evolution
肺癌演變過程中高可塑性細胞狀態的出現
Cancer cell
27
Epigenomic State Transitions Characterize Tumor Progression in Mouse Lung Adenocarcinoma
表觀基因組狀態轉變表徵小鼠肺腺癌的腫瘤進展
Cancer cell
27
Studying Lineage Plasticity One Cell at a Time
逐個細胞研究譜系可塑性
Circulation
24
A Reservoir of Fibroblasts Promotes Recovery from Limb Ischemia
成纖維細胞庫促進肢體缺血恢復
Circulation
24
Environment-Sensing Aryl Hydrocarbon Receptor Inhibits the Chondrogenic Fate of Modulated Smooth Muscle Cells in Atherosclerotic Lesions
環境敏感的芳烴受體抑制動脈粥樣硬化病變中調製的平滑肌細胞的軟骨形成命運
Circulation
24
Phosphoinositide 3-Kinase-Regulated Pericyte Maturation Governs Vascular Remodeling
磷脂醯肌醇3-激酶調節的周細胞成熟調控血管重構
Immunity
23
Combinatorial Single-Cell Analyses of Granulocyte-Monocyte Progenitor Heterogeneity Reveals an Early Uni-potent Neutrophil Progenitor
粒-單核細胞祖細胞異質性的組合單細胞分析揭示了一個早期的單一功能的中性粒細胞祖細胞
Immunity
23
Differential IRF8 Transcription Factor Requirement Defines Two Pathways of Dendritic Cell Development in Humans
差異IRF8轉錄因子需求定義了人類樹突狀細胞發育的兩條途徑
Cell metabolism
22
Distinct iNKT Cell Populations Use IFNγ or ER Stress-Induced IL-10 to Control Adipose Tissue Homeostasis
應用幹擾素γ或內質網應激誘導的IL-10控制脂肪組織穩態的不同iNKT細胞群
Cell stem cell
21
Intrinsic Endocardial Defects Contribute to Hypoplastic Left Heart Syndrome
先天性心內膜缺損導致左心發育不良症候群
Cell stem cell
21
Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo
下一代代孕WNT支持體內有機體生長和解旋捲曲多效性
Cell stem cell
21
Resolving Fates and Single-Cell Transcriptomes of Hematopoietic Stem Cell Clones by PolyloxExpress Barcoding
用PolyloxExpress條形碼解析造血幹細胞克隆的命運和單細胞轉錄
Cell stem cell
21
Single-Cell Analysis of Neonatal HSC Ontogeny Reveals Gradual and Uncoordinated Transcriptional Reprogramming that Begins before Birth
新生兒HSC個體發育的單細胞分析揭示了出生前開始的漸進和不協調的轉錄重編程
Accounts of chemical research
21
Magnetic Ranking Cytometry: Profiling Rare Cells at the Single-Cell Level
磁排序法：在單細胞水平分析稀有細胞
Nature immunology
20
Mapping systemic lupus erythematosus heterogeneity at the single-cell level
在單細胞水平繪製系統性紅斑狼瘡異質性圖譜
Nature immunology
20
Single-cell landscape of immunological responses in patients with COVID-19
新冠肺炎患者免疫應答的單細胞圖譜
Nature immunology
20
The mesenchymal context in inflammation, immunity and cancer
炎症、免疫和癌症中的間質環境
Nature reviews. Cardiology
20
Single-cell RNA sequencing in cardiovascular development, disease and medicine
單細胞RNA測序在心血管發育、疾病和醫學中的應用
Nature neuroscience
20
A community-based transcriptomics classification and nomenclature of neocortical cell types
基於種群的轉錄組學分類和新皮層細胞類型命名
Nature cell biology
20
Cell-cell adhesion and 3D matrix confinement determine jamming transitions in breast cancer invasion
細胞粘附和三維基質限制決定乳腺癌侵襲的幹擾轉變
Nature cell biology
20
Cell-cell adhesion and 3D matrix confinement determine jamming transitions in breast cancer invasion
細胞-細胞粘附和3D基質限制決定乳腺癌侵襲過程中的幹擾轉變
Nature cell biology
20
Persistence of a regeneration-associated, transitional alveolar epithelial cell state in pulmonary fibrosis
再生相關的過渡性肺泡上皮細胞狀態在肺纖維化中的持續性
Nature cell biology
20
Robust gene expression programs underlie recurrent cell states and phenotype switching in melanoma
強健的基因表達程序是黑色素瘤復發細胞狀態和表型轉換的基礎
Nature biomedical engineering
19
Integrated pipeline for the accelerated discovery of antiviral antibody therapeutics
加速發現抗病毒抗體治療藥物的綜合流水線
Nature biomedical engineering
19
Whole-body tracking of single cells via positron emission tomography
正電子發射斷層掃描技術在單細胞全身示蹤中的應用
Blood
18
Developmental trajectory of prehematopoietic stem cell formation from endothelium
內皮細胞形成造血前幹細胞的發育軌跡
Blood
18
Glycolytic metabolism of pathogenic T cells enables early detection of GvHD by 13C-MRI
致病T細胞糖酵解代謝使13C-MRI早期發現移植物抗宿主病
Blood
18
Single-cell DNA amplicon sequencing reveals clonal heterogeneity and evolution in T-cell acute lymphoblastic leukemia
單細胞DNA擴增序列顯示T細胞急性淋巴細胞白血病的克隆異質性和進化
Gastroenterology
17
Single-Cell Analyses of Colon and Blood Reveal Distinct Immune Cell Signatures of Ulcerative Colitis and Crohn's Disease
結腸和血液的單細胞分析顯示潰瘍性結腸炎和克羅恩病有明顯的免疫細胞特徵
Gastroenterology
17
Single Cell Transcriptional Analyses Identify Lineage-Specific Epithelial Responses to Inflammation and Metaplastic Development in the Gastric Corpus
單細胞轉錄分析確定胃體炎症和化生發展的譜系特異性上皮反應
Gastroenterology
17
Single-Cell Analyses of Colon and Blood Reveal Distinct Immune Cell Signatures of Ulcerative Colitis and Crohn's Disease
結腸和血液的單細胞分析顯示潰瘍性結腸炎和克羅恩病不同的免疫細胞特徵
Gastroenterology
17
Succinate Produced by Intestinal Microbes Promotes Specification of Tuft Cells to Suppress Ileal Inflammation
腸道微生物產生的琥珀酸促進簇狀細胞特化以抑制迴腸炎症
Gastroenterology
17
Use of Single-Cell -Omic Technologies to Study the Gastrointestinal Tract and Diseases, From Single Cell Identities to Patient Features
應用單細胞組學技術研究胃腸道和疾病，從單細胞特性到患者特徵
Science translational medicine
16
Mapping cancer genetics at single-cell resolution
以單細胞解析度繪製癌症遺傳學圖譜
Nature microbiology
16
Single-cell RNA-sequencing reports growth-condition-specific global transcriptomes of individual bacteria
單細胞RNA測序報告單個細菌的特定生長條件的全球轉錄本
Hepatology (Baltimore, Md.)
15
Hsd17b13 Deficiency Does not Protect Mice From Obesogenic Diet Injury
Hsd17b13缺乏對小鼠肥胖性飲食損傷的保護作用
Hepatology (Baltimore, Md.)
15
le Cell Analysis for the Study of Liver Pathobiology
單細胞分析在肝臟病理生物學研究中的作用
Journal of the American Chemical Society
15
Fluorescent Droplet Cytometry for On-Cell Phenotype Tracking
螢光滴狀細胞術在細胞表型追蹤中的應用
Journal of the American Chemical Society
15
Ultrasensitive Detection of Enzymatic Activity Using Single Molecule Arrays
採用單分子晶片技術進行酶活性的超敏檢測
Circulation research
14
Dynamics of Cardiac Neutrophil Diversity in Murine Myocardial Infarction
小鼠心肌梗死心肌中性粒細胞多樣性的動態變化
Neuron
14
A Distributed Neural Code in the Dentate Gyrus and in CA1
齒狀回和CA1的分布式神經編碼
Neuron
14
CD49f Is a Novel Marker of Functional and Reactive Human iPSC-Derived Astrocytes
CD49f是人類iPSC衍生星形膠質細胞功能性和反應性的新標誌物
Neuron
14
Dual-Color Single-Cell Imaging of the Suprachiasmatic Nucleus Reveals a Circadian Role in Network Synchrony
對視交叉上核的雙色單細胞成像揭示了網絡同步的晝夜節律作用
Neuron
14
Synthesis of Conserved Odor Object Representations in a Random, Divergent-Convergent Network
在一個隨機發散-收斂網絡中保守性氣味表徵的形成
Neuron
14
Transcriptional Reprogramming of Distinct Peripheral Sensory Neuron Subtypes after Axonal Injury
軸突損傷後不同周圍感覺神經元亞型的轉錄重編程
Trends in biotechnology
14
The Importance of Computational Modeling in Stem Cell Research
幹細胞研究中計算模模型的重要性分析
Signal transduction and targeted therapy
13
Adaptive immune responses to SARS-CoV-2 infection in severe versus mild individuals
重症與輕度SARS-CoV-2感染的適應性免疫應答
Science immunology
13
Heterogeneity and clonal relationships of adaptive immune cells in ulcerative colitis revealed by single-cell analyses
單細胞分析揭示潰瘍性結腸炎適應性免疫細胞的異質性和克隆關係
Science immunology
13
Pathogen-induced tissue-resident memory T(H)17 (T(RM)17) cells amplify autoimmune kidney disease
病原體誘導的組織駐留記憶T（H）17（T（RM）17）細胞擴增自身免疫性腎臟疾病
Trends in immunology
13
Microglia and Astrocytes in Disease: Dynamic Duo or Partners in Crime?
小膠質細胞和星形膠質細胞在疾病：活躍的搭檔或幫兇？
Trends in immunology
13
Understanding Normal and Malignant Human Hematopoiesis Using Next-Generation Humanized Mice
通過二代測序人源化的小鼠進行人正常及惡性造血功能的研究
Science advances
13
Cellular diversity of the regenerating caudal fin
再生尾鰭的細胞多樣性
Science advances
13
Life span extension by glucose restriction is abrogated by methionine supplementation: Cross-talk between glucose and methionine and implication of methionine as a key regulator of life span
通過限制葡萄糖延長壽命被補充蛋氨酸所廢除：葡萄糖和蛋氨酸之間的相互作用以及蛋氨酸作為壽命關鍵調節器的含義
Science advances
13
Social reprogramming in ants induces longevity-associated glia remodeling
螞蟻的社交重塑誘導長壽相關的神經膠質重塑
Molecular psychiatry
12
Developmental excitation-inhibition imbalance underlying psychoses revealed by single-cell analyses of discordant twins-derived cerebral organoids
單細胞分析揭示精神病基礎上的發育性興奮抑制失衡
The European respiratory journal
12
Elevated ACE2 expression in the olfactory neuroepithelium: implications for anosmia and upper respiratory SARS-CoV-2 entry and replication
嗅神經上皮ACE2表達增高：嗅覺缺失和上呼吸道SARS-CoV-2進入和複製的意義
Nature communications
12
A clustering-independent method for finding differentially expressed genes in single-cell transcriptome data
一種在單細胞轉錄組數據中尋找差異表達基因的聚類獨立方法
Nature communications
12
A single-cell atlas of the human substantia nigra reveals cell-specific pathways associated with neurological disorders
人類黑質的單細胞圖譜揭示了與神經疾病相關的細胞特異性通路。
Nature communications
12
Antibody-secreting cell destiny emerges during the initial stages of B-cell activation
抗體分泌細胞的命運出現在B細胞活化的最初階段
Nature communications
12
Author Correction: Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy
作者更正：單細胞RNA序列揭示膠質母細胞瘤重演正常的神經發育層次
Nature communications
12
Cardiac dopamine D1 receptor triggers ventricular arrhythmia in chronic heart failure
心臟多巴胺D1受體誘發慢性心力衰竭室性心律失常
Nature communications
12
Cellular and molecular properties of neural progenitors in the developing mammalian hypothalamus
哺乳動物下丘腦發育過程中神經祖細胞的細胞和分子特性
Nature communications
12
Distinct fibroblast subsets regulate lacteal integrity through YAP/TAZ-induced VEGF-C in intestinal villi
不同的成纖維細胞亞群通過YAP/TAZ誘導的腸絨毛VEGF-C調節乳汁的完整性
Nature communications
12
Elucidating the fundamental fibrotic processes driving abdominal adhesion formation
基本的纖維化過程驅動腹部粘連的形成
Nature communications
12
Frataxin gene editing rescues Friedreich's ataxia pathology in dorsal root ganglia organoid-derived sensory neurons
Frataxin基因編輯對Friedreich共濟失調病理的修復作用
Nature communications
12
Gene editing and elimination of latent herpes simplex virus in vivo
體內潛伏單純皰疹病毒的基因編輯和消除
Nature communications
12
High throughput error corrected Nanopore single cell transcriptome sequencing
高通量糾錯納米孔單細胞轉錄組測序
Nature communications
12
Loss of NARS1 impairs progenitor proliferation in cortical brain organoids and leads to microcephaly
NARS1缺失會損害皮質類腦器官的祖細胞增殖，導致小頭畸形
Nature communications
12
Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action
利用多重單細胞轉錄反應譜分析，定義癌症易感性和治療作用機制
Nature communications
12
Single cell electron collectors for highly efficient wiring-up electronic abiotic/biotic interfaces
用於高效連接非生物/生物電子接口的單電池電子收集器
Nature communications
12
Single cell RNA sequencing identifies early diversity of sensory neurons forming via bi-potential intermediates
單細胞RNA測序鑑定通過雙電位中間體形成的感覺神經元的早期多樣性
Nature communications
12
Single cell transcriptomics comes of age
單細胞轉錄組學已經成熟
Nature communications
12
Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis
單細胞轉錄組學鑑定前腸器官發生過程中協調內胚層和中胚層多樣化的信號網絡
Nature communications
12
Single cell transcriptomics of human epidermis identifies basal stem cell transition states
人表皮的單細胞轉錄組學可確定基礎幹細胞的過渡狀態
Nature communications
12
Single-cell analysis of two severe COVID-19 patients reveals a monocyte-associated and tocilizumab-responding cytokine storm
對兩名嚴重COVID-19患者的單細胞分析顯示單核細胞相關和託珠單抗反應的細胞因子風暴
Nature communications
12
Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination
單細胞分析揭示了成纖維細胞的異質性以及成纖維細胞和壁細胞鑑定和區分的標準
Nature communications
12
Single-cell RNA sequencing identifies shared differentiation paths of mouse thymic innate T cells
單細胞RNA測序可識別小鼠胸腺先天T細胞的共有分化途徑
Nature communications
12
Single-cell TCR sequencing reveals phenotypically diverse clonally expanded cells harboring inducible HIV proviruses during ART
單細胞TCR測序揭示了在ART期間攜帶可誘導的HIV前病毒的表型多樣的克隆細胞
Nature communications
12
Single-neuron representation of learned complex sounds in the auditory cortex
在聽神經皮層中，關於學會複雜聲音的單神經元活動
Nature communications
12
The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development
從胚胎發育到出生後晚期下丘腦模式和分化的細胞和分子圖譜
Nature communications
12
Wnt activation as a therapeutic strategy in medulloblastoma
激活Wnt蛋白是成神經管細胞瘤的一種治療策略
Molecular plant
12
Global Dynamic Molecular Profiling of Stomatal Lineage Cell Development by Single-Cell RNA Sequencing
氣孔譜系細胞發育的單細胞RNA序列分析
Nucleic acids research
12
Toward a translationally independent RNA-based synthetic oscillator using deactivated CRISPR-Cas
使用失活的CRISPR-Cas實現翻譯獨立的基於RNA的合成振蕩器
Nucleic acids research
12
Uncoupling gene expression noise along the central dogma using genome engineered human cell lines
使用基因組改造的人類細胞系消除中心法則的基因表達噪聲
Small (Weinheim an der Bergstrasse, Germany)
11
One Cell, One Drop, One Click: Hybrid Microfluidics for Mammalian Single Cell Isolation
一個細胞，一滴，一鍵: 用於哺乳動物單細胞分離的混合微流控技術
Brain : a journal of neurology
11
Clinical and experimental insight into pathophysiology, comorbidity and therapy of absence seizures
對於失神發作的病理生理學、併發症及治療方法的臨床和實驗見解
Trends in genetics : TIG
11
Elucidation of Biological Networks across Complex Diseases Using Single-Cell Omics
採用單細胞組學解析複雜疾病的生物網絡
Nano letters
11
Label-Free and Three-Dimensional Visualization Reveals the Dynamics of Plasma Membrane-Derived Extracellular Vesicles
無標籤和三維可視化揭示了血漿膜衍生的細胞外囊泡的動力學。
Annual review of genetics
11
Measuring and Modeling Single-Cell Heterogeneity and Fate Decision in Mouse Embryos
小鼠胚胎中的單細胞異質性和命運決定測量和建模
Genome research
11
RNA-Bloom enables reference-free and reference-guided sequence assembly for single-cell transcriptomes
RNA-Bloom為單細胞轉錄組提供了無參考和參考引導的序列組裝
Seminars in cancer biology
11
Epigenomic technologies for precision oncology
表觀基因組技術在精準腫瘤學中的應用
Genome biology
11
A systematic evaluation of single-cell RNA-sequencing imputation methods
關於單細胞RNA測序缺失值處理方法的系統性評估
Genome biology
11
Assessment of statistical methods from single cell, bulk RNA-seq, and metagenomics applied to microbiome data
對於微生物單細胞、群體性細胞RNA測序及宏基因組數據的統計分析方法的評估
Genome biology
11
Demystifying "drop-outs" in single-cell UMI data
揭秘單細胞RNA測序數據中UMI的「缺失」
Genome biology
11
Integrative analyses of single-cell transcriptome and regulome using MAESTRO
採用MAESTRO綜合分析單細胞轉錄組和調控組
Genome biology
11
Knowledge-primed neural networks enable biologically interpretable deep learning on single-cell sequencing data
基於知識的神經網絡能夠對單細胞測序數據進行生物可解釋的深度學習
Genome biology
11
Methods for copy number aberration detection from single-cell DNA-sequencing data
單細胞DNA測序數據中拷貝數變異檢測的分析方法
Genome biology
11
Tuning parameters of dimensionality reduction methods for single-cell RNA-seq analysis
用於單細胞RNA序列分析的降維方法的調整參數
Ageing research reviews
11
Discovery of new epigenomics-based biomarkers and the early diagnosis of neurodegenerative diseases
新的表觀基因組學生物標誌物的發現和神經退行性疾病的早期診斷
American journal of human genetics
11
Human iPSC Modeling Reveals Mutation-Specific Responses to Gene Therapy in a Genotypically Diverse Dominant Maculopathy
人誘導多能幹細胞模型揭示了遺傳多樣性顯性黃斑病變的基因治療的突變特異性反應
Nature protocols
10
Bacterial mock communities as standards for reproducible cytometric microbiome analysis
細菌模擬群落是微生物可重複的細胞分析的標準
Nature protocols
10
Dynamic single-cell phenotyping of immune cells using the microfluidic platform DropMap
通過微流體平臺 DropMap分析免疫細胞的動態單細胞表型
Nature protocols
10
Single-cell imaging of human cancer xenografts using adult immunodeficient zebrafish
通過成熟的免疫缺陷斑馬魚對人類腫瘤異種移植物進行單細胞成像
Biomaterials
10
Modulation of Wnt and Activin/Nodal supports efficient derivation, cloning and suspension expansion of human pluripotent stem cells
Wnt 和激活素/結節蛋白的調控促進人多能幹細胞的有效分化、克隆和懸浮擴增
Neuro-oncology
10
Modeling glioblastoma invasion using human brain organoids and single-cell transcriptomics
使用人腦類器官和單細胞轉錄組學建立膠質母細胞瘤侵襲模型
Clinical cancer research : an official journal of the American Association for
Cancer Research
10
A20 and RBX1 Regulate Brentuximab Vedotin Sensitivity in Hodgkin Lymphoma Models
A20 和 RBX1 調節霍奇金淋巴瘤模型中Brentuximab Vedotin的敏感性
Clinical cancer research : an official journal of the American Association for
Cancer Research
10
Changes in peripheral and local tumor immunity after neoadjuvant chemotherapy reshape clinical outcomes in patients with breast cancer
新輔助化療後周圍和局部腫瘤免疫的變化重塑乳腺癌患者的臨床結果
Clinical cancer research : an official journal of the American Association for
Cancer Research
10
Single-Cell Circulating Tumor Cell Analysis Reveals Genomic Instability as a Distinctive Feature of Aggressive Prostate Cancer
單細胞外周循環腫瘤細胞分析顯示基因組不穩定性是侵襲性前列腺癌的一個顯著特徵
Clinical cancer research : an official journal of the American Association for
Cancer Research
10
The Outcome of Ex Vivo TIL Expansion Is Highly Influenced by Spatial Heterogeneity of the Tumor T-Cell Repertoire and Differences in Intrinsic In Vitro Growth Capacity between T-Cell Clones
體內TIL擴增的結果在很大程度上受腫瘤T細胞庫的空間異質性以及T細胞克隆之間的固有體外生長能力差異的影響
Developmental cell
10
Single-Cell RNA Sequencing of Human, Macaque, and Mouse Testes Uncovers Conserved and Divergent Features of Mammalian Spermatogenesis
人類、獼猴和小鼠睪丸的單細胞RNA測序揭示了哺乳動物精子發生的保守和不同特徵
Developmental cell
10
Differentiation of Human Intestinal Organoids with Endogenous Vascular Endothelial Cells
內源性血管內皮細胞分化為人腸道類器官
Developmental cell
10
Modulation of the Promoter Activation Rate Dictates the Transcriptional Response to Graded BMP Signaling Levels in the Drosophila Embryo
啟動子激活率的調節決定了果蠅胚胎中對分級BMP信號水平的轉錄反應
Developmental cell
10
Single-Cell RNA Sequencing of the Cynomolgus Macaque Testis Reveals Conserved Transcriptional Profiles during Mammalian Spermatogenesis
食蟹獼猴睪丸的單細胞RNA測序揭示了哺乳動物精子發生過程中的保守轉錄圖譜
Redox biology
10
Retinal homeostasis and metformin-induced protection are not affected by retina-specific Pparδ knockout
視網膜穩態和二甲雙胍誘導的保護不受視網膜特異性Pparδ敲除的影響
Journal for immunotherapy of cancer
10
Anti-tumor effects of NK cells and anti-PD-L1 antibody with antibody-dependent cellular cytotoxicity in PD-L1-positive cancer cell lines
NK細胞和抗PD-L1抗體在PD-L1陽性癌細胞系中具有抗體依賴性細胞毒性的抗腫瘤作用
Journal for immunotherapy of cancer
10
Subtype and grade-dependent spatial heterogeneity of T-cell infiltration in pediatric glioma
小兒神經膠質瘤T細胞浸潤的亞型和等級依賴性空間異質性
The EMBO journal
10
Complex IV subunit isoform COX6A2 protects fast-spiking interneurons from oxidative stress and supports their function
複雜的IV亞基同工型COX6A2可保護快速加標的中間神經免受氧化應激並支持其功能
The EMBO journal
10
Stromal cell diversity associated with immune evasion in human triple-negative breast cancer
人三陰性乳腺癌中與免疫逃避相關的基質細胞多樣性
Cancer research
10
Morphology-predicted large scale transition number in circulating tumor cells identifies a chromosomal instability biomarker associated with poor outcome in castration-resistant prostate cancer
形態預測的循環腫瘤細胞中的大規模轉移數可鑑定與去勢抵抗性前列腺癌預後不良相關的染色體不穩定生物標誌物
Cancer research
10
Multi-omic analysis of subtype evolution and heterogeneity in high-grade serous ovarian carcinoma
高度漿液性卵巢癌亞型進化和異質性的多組學分析
Proceedings of the National Academy of Sciences of the United States of America
9
A pathogenic and clonally expanded B cell transcriptome in active multiple sclerosis
活動期多發性硬化症的致病性和克隆性擴增的B細胞轉錄組
Proceedings of the National Academy of Sciences of the United States of America
9
A robust and interpretable end-to-end deep learning model for cytometry data
強大且可解釋的端到端深度學習細胞計數數據模型
Proceedings of the National Academy of Sciences of the United States of America
9
A single-cell Raman-based platform to identify developmental stages of human pluripotent stem cell-derived neurons
一種基於單細胞拉曼的鑑定人多能幹細胞源性神經元發育階段的平臺
Proceedings of the National Academy of Sciences of the United States of America
9
Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens
構象多樣性促進抗體突變軌跡以及外源和自身抗原之間的區分
Proceedings of the National Academy of Sciences of the United States of America
9
Fungal biofilm architecture produces hypoxic microenvironments that drive antifungal resistance
真菌生物膜結構產生缺氧的微環境，可驅動抗真菌性
Proceedings of the National Academy of Sciences of the United States of America
9
Heterogeneous origins and functions of mouse skeletal muscle-resident macrophages
小鼠骨骼肌駐留巨噬細胞的異質起源和功能
Proceedings of the National Academy of Sciences of the United States of America
9
Metabolic stress promotes stop-codon readthrough and phenotypic heterogeneity
代謝應激促進終止密碼子通讀和表型異質性
Proceedings of the National Academy of Sciences of the United States of America
9
Multidimensional study of the heterogeneity of leukemia cells in t(8;21) acute myelogenous leukemia identifies the subtype with poor outcome
對t（8; 21）急性骨髓性白血病中白血病細胞異質性的多維研究確定了不良預後的亞型
Proceedings of the National Academy of Sciences of the United States of America
9
Reproductive outcomes predicted by phase imaging with computational specificity of spermatozoon ultrastructure
通過相位成像預測精子超微結構的計算結果的生殖結果
Proceedings of the National Academy of Sciences of the United States of America
9
Single-cell RNA-seq analysis revealed long-lasting adverse effects of tamoxifen on neurogenesis in prenatal and adult brains
單細胞RNA-seq分析顯示他莫昔芬對產前和成年大腦神經發生的長期不良影響
Proceedings of the National Academy of Sciences of the United States of America
9
Spatiotemporal mapping of bacterial membrane potential responses to extracellular electron transfer
細菌膜電位對細胞外電子轉移的時空映射
Proceedings of the National Academy of Sciences of the United States of America
9
Stochastic bacterial population dynamics restrict the establishment of antibiotic resistance from single cells
隨機細菌種群動態限制了單細胞對抗生素耐藥性的建立
Proceedings of the National Academy of Sciences of the United States of America
9
Visualization of human T lymphocyte-mediated eradication of cancer cells in vivo
人T淋巴細胞介導的體內消滅癌細胞的可視化
Proceedings of the National Academy of Sciences of the United States of America
9
Wide lag time distributions break a trade-off between reproduction and survival in bacteria
較寬的滯後時間分布打破了細菌繁殖與存活之間的權衡
Proceedings of the National Academy of Sciences of the United States of America
9
β2 Integrins differentially regulate γδ T cell subset thymic development and peripheral maintenance
β2整合素差異性調節γδT細胞亞群的胸腺發育和外周維持
Medicinal research reviews
9
Reinvigorating exhausted CD8(+) cytotoxic T lymphocytes in the tumor microenvironment and current strategies in cancer immunotherapy
在腫瘤微環境中重振筋疲力盡的CD8（+）細胞毒性T淋巴細胞和癌症免疫治療的當前策略
Journal of the American Society of Nephrology : JASN
9
Integration of GWAS Summary Statistics and Gene Expression Reveals Target Cell Types Underlying Kidney Function Traits
GWAS摘要統計和基因表達的整合揭示了腎功能特徵背後的靶細胞類型
The ISME journal
9
Intracellular amorphous Ca-carbonate and magnetite biomineralization by a magnetotactic bacterium affiliated to the Alphaproteobacteria
α變形桿菌屬趨磁細菌對細胞內無定形碳酸鈣和磁鐵礦的生物礦化作用
Water research
9
Application of purple phototrophic bacteria in a biofilm photobioreactor for single cell protein production: Biofilm vs suspended growth
紫色光養細菌在生物膜光生物反應器中用於單細胞蛋白質生產的應用：生物膜與懸浮生長
Water research
9
Genotoxic activities of wastewater after ozonation and activated carbon filtration: Different effects in liver-derived cells and bacterial indicators
臭氧和活性炭過濾後廢水的遺傳毒性活動：對肝源細胞和細菌指標的不同影響
Journal of hazardous materials
9
Exposure to bisphenol analogues interrupts growth, proliferation, and fatty acid compositions of protozoa Tetrahymena thermophila
暴露於雙酚類似物會破壞原生動物四膜蟲嗜熱菌的生長，增殖和脂肪酸組成