序號
雜誌
IF
英文題目
中文題目
1
Lancet
60.392
Predicting erenumab adverse events with single-cell genomics
應用單細胞基因組學預測erenumab的不良反應
2
Nat Rev Cancer
53.03
The dormant cancer cell life cycle
處於休眠狀態的癌細胞生命周期
3
Nature
42.778
A single-cell transcriptomic atlas characterizes ageing tissues in the mouse
單細胞轉錄圖譜描述了小鼠衰老組織的特徵。
4
Nature
42.778
Ageing hallmarks exhibit organ-specific temporal signatures
衰老特徵顯示器官特異性的時間標誌物
5
Nature
42.778
Distinct subnetworks of the thalamic reticular nucleus
丘腦網狀核的不同亞網絡
6
Nature
42.778
Epigenetic regulator function through mouse gastrulation
小鼠原腸胚形成的表觀遺傳調節功能
7
Nature
42.778
Mechanisms of stretch-mediated skin expansion at single-cell resolution
單細胞解析度下拉伸介導的皮膚擴張機制
8
Nature
42.778
Pervasive lesion segregation shapes cancer genome evolution
普遍的病變分離塑造癌症基因組進化
9
Nature
42.778
Signalling input from divergent pathways subverts B cell transformation
不同信號通路的輸入破壞了B細胞轉化
10
Nature
42.778
Single-cell lineage tracing unveils a role for TCF15 in haematopoiesis
單細胞譜系追蹤揭示了 TCF15在造血中的作用
11
Nature
42.778
The changing mouse embryo transcriptome at whole tissue and single-cell resolution
小鼠胚胎轉錄組在全組織和單細胞解析度上的變化
12
Science
41.845
A programmable fate decision landscape underlies single-cell aging in yeast
酵母中單細胞老化的可編程命運決定圖譜
13
Science
41.845
Cancer cells deploy lipocalin-2 to collect limiting iron in leptomeningeal metastasis
癌細胞利用lipocalin-2在軟腦膜轉移中收集限制性鐵
14
Science
41.845
Human CNS barrier-forming organoids with cerebrospinal fluid production
人中樞神經系統屏障形成類器官與腦脊液生成
15
Science
41.845
Human fetal microglia acquire homeostatic immune-sensing properties early in development
人胎兒小膠質細胞在發育早期獲得穩態免疫感應特性
16
Cell
38.637
Memory Sequencing Reveals Heritable Single-Cell Gene Expression Programs Associated with Distinct Cellular Behaviors
記憶測序揭示與不同細胞行為相關的可遺傳單細胞基因表達程序
17
Cell
38.637
Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition
小膠質細胞需要CD4 T細胞來完成胎兒到成人的轉變
18
Cell
38.637
Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma
人鱗狀細胞癌成分和空間結構的多模態分析
19
Cell
38.637
Pathogenic Mechanisms of Somatic Mutation and Genome Mosaicism in Aging
衰老過程中體細胞突變和基因組嵌合體的致病機制
20
Cell
38.637
Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients' B Cells
通過對恢復期患者B細胞的高通量單細胞測序鑑定抗SARS-CoV-2的強中和抗體
21
Cell
38.637
Self-Reporting Transposons Enable SimultaneousReadout of Gene Expression and Transcription Factor Binding in Single Cells
自我報告轉座子能夠同時讀出單細胞中的基因表達和轉錄因子結合
22
Nat Biotechnol
36.558
Cell type prioritization in single-cell data
細胞類型在單細胞數據中的優化
23
Nat Med
36.13
A single-cell atlas of the peripheral immune response in patients with severe COVID-19
重症新冠肺炎患者COVID-19外周免疫反應的單細胞圖譜
24
Nat Rev Genet
33.133
Lineage tracing meets single-cell omics: opportunities and challenges
譜系追蹤與單細胞組學：機遇與挑戰
25
Nat Methods
30.822
Cumulus provides cloud-based data analysis for large-scale single-cell and single-nucleus RNA-seq
Cumulus為大規模單細胞和單核RNA-seq提供基於雲的數據分析
26
Nat Methods
30.822
Improving single-cell RNA counting
單細胞RNA計數方法的改進
27
Nat Methods
30.822
Investigating higher-order interactions in single-cell data with scHOT
使用scHOT研究單細胞數據中的更高指令交流
28
Nat Methods
30.822
ZipSeq: barcoding for real-time mapping of single cell transcriptomes
ZipSeq：用於單細胞轉錄組實時映射的barcoding
29
Cancer Discov
29.497
Tumor Microenvironment Is Critical for the Maintenance of Cellular States Found in Primary Glioblastomas
腫瘤微環境對於原發性膠質母細胞瘤中細胞狀態的維持至關重要
30
Cancer Discov
29.497
Utility of Human-Derived Models for Glioblastoma
人源性膠質母細胞瘤模型的應用
31
Nat Genet
27.603
Imprecise DNMT1 activity coupled with neighbor-guided correction enables robust yet flexible epigenetic inheritance
不精確的DNMT1活性與鄰居引導的校正相結合，可以實現穩健而靈活的表觀遺傳基因組
32
Nat Genet
27.603
Single-cell analysis of clonal maintenance of transcriptional and epigenetic states in cancer cells
癌細胞表觀組和基因組狀態克隆維持的單細胞分析
33
Cancer Cell
26.602
Cytotoxic CD4(+) T Cells in Bladder Cancer-A New License to Kill
膀胱癌中的細胞毒性CD4(+)T細胞--一種新的殺滅許可證
34
Cancer Cell
26.602
Emergence of a High-Plasticity Cell State during Lung Cancer Evolution
肺癌演變過程中高可塑性細胞狀態的發生
35
Cancer Cell
26.602
Epigenomic State Transitions Characterize Tumor Progression in Mouse Lung Adenocarcinoma
表觀基因組狀態轉變表徵小鼠肺腺癌的腫瘤進展
36
Cancer Cell
26.602
MYC Drives Temporal Evolution of Small Cell Lung Cancer Subtypes by Reprogramming Neuroendocrine Fate
MYC通過重新編程神經內分泌推動小細胞肺癌亞型的時間演示
37
Cancer Cell
26.602
Single-Cell Analyses in the Multi-omics Era
多組學時代的單細胞分析
38
Cancer Cell
26.602
Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma
單細胞RNA測序揭示小兒室管膜瘤的細胞層次結構和受損的發育軌跡
39
Cancer Cell
26.602
Sub-group, Sub-type, and Cell-type Heterogeneity of Ependymoma
室管膜瘤的亞群、亞型、細胞型的異質性
40
Circulation
23.603
Pathogenic Autoimmunity in Atherosclerosis Evolves from Initially Protective ApoB-Reactive CD4(+) T-Regulatory Cells
動脈粥樣硬化中的致病性自身免疫從最初的保護性ApoB響應CD4（+）T調節細胞演變而來
41
Circulation
23.603
Single-Cell RNA Sequencing to Dissect the Immunological Network of Autoimmune Myocarditis
單細胞RNA測序分析自身免疫性心肌炎的免疫網絡
42
Circulation
23.603
The Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis
幹細胞多能性基因Klf4和Oct4調節複雜的平滑肌細胞表型變化，在動脈粥樣硬化的晚期病變中起關鍵作用
43
Immunity
22.553
An Integrated Multi-omic Single-Cell Atlas of Human B Cell Identity
人類B細胞多組分單細胞圖譜的建立
44
Immunity
22.553
Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Kinase Transcriptional and Biochemical Function
複雜的自體炎症症候群揭示了JAK1激酶轉錄和生化功能的基本原理
45
Immunity
22.553
Differential IRF8 Transcription Factor Requirement Defines Two Pathways of Dendritic Cell Development in Humans
不同的IRF8轉錄因子需求決定了人類樹突狀細胞發育的兩條途徑
46
Cell Stem Cell
20.86
A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells
人類骨骼肌圖譜確定了幹細胞和祖細胞在整個發育過程中的軌跡，以及來自人類多能幹細胞的軌跡
47
Cell Stem Cell
20.86
Cell-by-Cell Deconstruction of Stem Cell Niches
幹細胞龕的逐細胞解構
48
Cell Stem Cell
20.86
Inflammatory Signals Induce AT2 Cell-Derived Damage-Associated Transient Progenitors that Mediate Alveolar Regeneration
炎症信號誘導AT2細胞源性損傷相關的短暫性祖細胞介導肺泡再生
49
Acc Chem Res
20.832
Magnetic Ranking Cytometry: Profiling Rare Cells at the Single-Cell Level
磁排序細胞術：在單細胞水平上分析稀有細胞
50
Nat Rev Nephrol
20.711
Tools for the analysis of high-dimensional single-cell RNA sequencing data
高維單細胞RNA測序數據分析工具
51
J Hepatol
20.582
Integrative molecular profiling of autoreactive CD4 T cells in autoimmune hepatitis
自身免疫性肝炎自身反應性CD4 T細胞的綜合分子分析
52
Cell Res
20.507
Comparative analysis of cell lineage differentiation during hepatogenesis in humans and mice at the single-cell transcriptome level
人和小鼠肝發生過程中細胞譜系分化的單細胞轉錄組水平比較分析
53
Cell Res
20.507
Single-cell transcriptomics reveals regulators underlying immune cell diversity and immune subtypes associated with prognosis in nasopharyngeal carcinoma
單細胞轉錄組學揭示了與鼻咽癌預後相關的免疫細胞多樣性和免疫亞型的潛在調控因子
54
Cell Res
20.507
Transdifferentiation of tumor infiltrating innate lymphoid cells during progression of colorectal cancer
大腸癌進展過程中腫瘤浸潤的固有淋巴樣細胞的轉分化
55
Nat Immunol
20.479
Novel Hexb-based tools for studying microglia in the CNS
用於研究中樞神經系統小膠質細胞的基於Hexb的新工具
56
Nat Immunol
20.479
Single-cell transcriptome profiling reveals neutrophil heterogeneity in homeostasis and infection
單細胞轉錄組譜分析揭示中性粒細胞在穩態和感染中的異質性
57
Nat Immunol
20.479
The activation trajectory of plasmacytoid dendritic cells in vivo during a viral infection
病毒感染期間體內漿細胞樣樹突狀細胞的激活軌跡
58
Nat Cell Biol
20.042
Dissecting intratumour heterogeneity of nodal B-cell lymphomas at the transcriptional, genetic and drug-response levels
淋巴結B細胞淋巴瘤在轉錄、遺傳和藥物反應水平上的腫瘤內異質性分析
59
Nat Cell Biol
20.042
Persistence of a regeneration-associated, transitional alveolar epithelial cell state in pulmonary fibrosis
肺纖維化中再生相關的移行性肺泡上皮細胞狀態的持續性
60
Gut
19.819
Genomic and transcriptomic profiling of carcinogenesis in patients with familial adenomatous polyposis
家族性腺瘤性息肉病患者致癌作用的基因組和轉錄組分析
61
Nat Phys
19.256
The role of single cell mechanical behavior and polarity in driving collective cell migration
單細胞機械行為和極性在驅動集體細胞遷移中的作用
62
Nat Biomed Eng
18.952
Tracking the expression of therapeutic protein targets in rare cells by antibody-mediated nanoparticle labelling and magnetic sorting
通過抗體介導的納米顆粒標記和磁性分選跟蹤治療性蛋白靶點在稀有細胞中的表達
63
Blood
17.543
Single cell analyses and machine learning define hematopoietic progenitor and HSC-like cells derived from human PSCs
單細胞分析和機器學習定義了源自人類PSC的造血祖細胞和HSC樣細胞
64
Blood
17.543
Single-cell genomics reveals the genetic and molecular bases for escape from mutational epistasis in myeloid neoplasms
單細胞基因組學揭示了髓系腫瘤逃避突變上位性的遺傳和分子基礎
65
Am J Respir Crit Care Med
17.452
A Single-cell Atlas of the Human Healthy Airways
人體健康氣道單細胞圖譜
66
Am J Respir Crit Care Med
17.452
Chemokine Receptor 2-targeted Molecular Imaging in Pulmonary Fibrosis
肺纖維化中趨化因子受體2靶向分子成像
67
Am J Respir Crit Care Med
17.452
Expression of the SARS-CoV-2 ACE2 Receptor in the Human Airway Epithelium
SARS-CoV-2 ACE2受體在人體氣道上皮中的表達
68
Am J Respir Crit Care Med
17.452
Single Cell Reconstruction of Human Basal Cell Diversity in Normal and IPF Lung
正常人和IPF肺基底細胞多樣性的單細胞重建
69
Am J Respir Crit Care Med
17.452
Single-cell RNA Expression Profiling of ACE2, The Receptor of SARS-CoV-2
SARS-CoV-2受體ACE2的單細胞RNA表達譜分析
70
Am J Respir Crit Care Med
17.452
Spelunking in Sputum: Single Cell RNA Sequencing Sheds New Insights into Cystic Fibrosis
痰的探索：單細胞RNA測序為囊性纖維化提供了新見識
71
Gastroenterology
17.373
Combination of PD-1 Inhibitor and OX40 Agonist Induces Tumor Rejection and Immune Memory in Mouse Models of Pancreatic Cancer
PD-1抑制劑與OX40激動劑聯合誘導胰腺癌小鼠模型的腫瘤排斥反應和免疫記憶
72
Gastroenterology
17.373
Increased Production of LIGHT by T Cells in Eosinophilic Esophagitis Promotes Differentiation of Esophageal Fibroblasts Toward an Inflammatory Phenotype
嗜酸性食管炎中T細胞產生的LIGHT增多，促進了食管成纖維細胞向炎性表型的分化。
73
Ann Rheum Dis
16.102
Quantitative planar array screen of 1000 proteins uncovers novel urinary protein biomarkers of lupus nephritis
1000種蛋白質的定量平面陣列篩選揭示了狼瘡性腎炎的新型尿蛋白生物標誌物
74
J Am Chem Soc
14.612
Counteranions in the Stimulation Solution Alter the Dynamics of Exocytosis Consistent with the Hofmeister Series
刺激液中的反陰離子改變了符合Hofmeister級數的胞吐作用動力學
75
J Am Chem Soc
14.612
DNA-Based Nanostructures for Live-Cell Analysis
用於活細胞分析的基於DNA的納米結構
76
ACS Nano
14.588
Hybrid Electro-Plasmonic Neural Stimulation with Visible-Light-Sensitive Gold Nanoparticles
可見光敏感金納米粒子複合電等離子體神經刺激
77
Circ Res
14.467
Impact of Local Allo-Immunity and Recipient Cells in Transplant Arteriosclerosis
局部同種免疫和受體細胞在移植性動脈硬化中的影響
78
Circ Res
14.467
Meta-Analysis of Leukocyte Diversity in Atherosclerotic Mouse Aortas
動脈粥樣硬化小鼠主動脈中白細胞多樣性的Meta分析
79
Circ Res
14.467
Regulatory T Cells License Macrophage Pro-Resolving Functions During Atherosclerosis Regression
動脈粥樣硬化消退過程中調節性T細胞許可巨噬細胞的促分解功能
80
Neuron
14.415
Cell-Type Specificity of Genomic Imprinting in Cerebral Cortex
大腦皮層基因組印跡的細胞類型特異性
81
Neuron
14.415
Extraction of Distinct Neuronal Cell Types from within a Genetically Continuous Population
從遺傳連續的族群中提取不同神經元類型
82
Trends Microbiol
13.546
Challenges of Studying the Human Virome - Relevant Emerging Technologies
人類病毒相關新興技術研究的挑戰
83
Signal Transduct Target Ther
13.493
Single cell transcriptome revealed SARS-CoV-2 entry genes enriched in colon tissues and associated with coronavirus infection and cytokine production
單細胞轉錄組研究揭示SARS-CoV-2病毒參與結腸組織的基因富集以及冠狀病毒感染與細胞因子產生的關聯性
84
Sci Immunol
13.44
Immunophenotyping of COVID-19 and influenza highlights the role of type I interferons in development of severe COVID-19
重症COVID-19研究進展中Ⅰ型幹擾素在COVID-19和流行感冒的免疫分型中扮演著突出的作用
85
Trends Immunol
13.422
Understanding Normal and Malignant Human Hematopoiesis Using Next-Generation Humanized Mice
利用下一代人源化小鼠了解正常和惡性人類造血
86
JAMA Cardiol
12.794
Association of Clonal Hematopoiesis of Indeterminate Potential With Inflammatory Gene Expression in Patients With Severe Degenerative Aortic Valve Stenosis or Chronic Postischemic Heart Failure
嚴重退行性主動脈瓣狹窄患者不確定潛在的克隆造血和炎症基因表達的研究
87
Annu Rev Neurosci
12.547
3D Brain Organoids: Studying Brain Development and Disease Outside the Embryo
3D腦器官:研究胚胎外的大腦發育和疾病
88
Nat Ecol Evol
12.541
Adaptation to low parasite abundance affects immune investment and immunopathological responses of cavefish
對低寄生蟲豐度的適應影響腔魚的免疫投入和免疫病理反應
89
J Cachexia Sarcopenia Muscle
12.511
Age-related decline of interferon-gamma responses in macrophage impairs satellite cell proliferation and regeneration
巨噬細胞中年齡相關的幹擾素-伽馬反應的下降會損害衛星細胞的增殖和再生
90
J Cachexia Sarcopenia Muscle
12.511
Single-cell deconstruction of post-sepsis skeletal muscle and adipose tissue microenvironments
膿毒症後骨骼肌和脂肪組織微環境的單細胞解構
91
Mol Psychiatry
12.384
Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids
線粒體肽酶PITRM1功能喪失誘導蛋白毒性應激和類阿爾茨海默病樣病理改變
92
Nat Commun
12.121
A molecular map of murine lymph node blood vascular endothelium at single cell resolution
小鼠淋巴結血管內皮細胞單細胞分辨分子圖
93
Nat Commun
12.121
Accelerated single cell seeding in relapsed multiple myeloma
加速單細胞接種治療復發性多發性骨髓瘤
94
Nat Commun
12.121
Alveolar regeneration through a Krt8+ transitional stem cell state that persists in human lung fibrosis
持續存在於人肺纖維化的Krt8+過渡幹細胞狀態下的肺泡再生
95
Nat Commun
12.121
An OTX2-PAX3 signaling axis regulates Group 3 medulloblastoma cell fate
OTX2-PAX3信號軸調控第3組髓母細胞瘤細胞命運
96
Nat Commun
12.121
Emerging heterogeneous compartments by viruses in single bacterial cells
單個細菌細胞中病毒形成的異質性隔室
97
Nat Commun
12.121
Flexible experimental designs for valid single-cell RNA-sequencing experiments allowing batch effects correction
靈活的實驗設計，有效的單細胞RNA測序實驗允許批量效應校正
98
Nat Commun
12.121
Histone deacetylase 3 controls lung alveolar macrophage development and homeostasis
組蛋白去乙醯化酶3控制肺泡巨噬細胞的發育和穩態
99
Nat Commun
12.121
Murine models of IDH-wild-type glioblastoma exhibit spatial segregation of tumor initiation and manifestation during evolution
IDH野生型膠質母細胞瘤的小鼠模型顯示腫瘤發生和發展過程中的空間分離
100
Nat Commun
12.121
Polymer physics indicates chromatin folding variability across single-cells results from state degeneracy in phase separation
聚合物物理表明，單細胞染色質摺疊變化是由於相分離過程中的狀態退化造成的
101
Nat Commun
12.121
Searching large-scale scRNA-seq databases via unbiased cell embedding with Cell BLAST
通過無偏置細胞嵌入細胞母細胞來搜索大規模的scRNA-seq資料庫
102
Nat Commun
12.121
Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy
單細胞RNA-seq顯示膠質母細胞瘤概括了一個正常的神經發育層次
103
Nat Commun
12.121
Single-cell transcriptomic analysis in a mouse model deciphers cell transition states in the multistep development of esophageal cancer
小鼠模型的單細胞轉錄組學分析揭示了食管癌多階段發展過程中的細胞過渡狀態
104
Nat Commun
12.121
Tumors induce de novo steroid biosynthesis in T cells to evade immunity
腫瘤誘導T細胞從頭合成類固醇以逃避免疫
105
Nat Commun
12.121
VoPo leverages cellular heterogeneity for predictive modeling of single-cell data
VoPo利用細胞異質性對單細胞數據進行預測建模
106
Nucleic Acids Res
11.501
Analyzing pre-symptomatic tissue to gain insights into the molecular and mechanistic origins of late-onset degenerative trinucleotide repeat disease
分析症狀前組織以深入了解遲發性退行性三核苷酸重複性疾病的分子和機制
107
Nucleic Acids Res
11.501
ASAP 2020 update: an open, scalable and interactive web-based portal for (single-cell) omics analyses
ASAP 2020更新：一個開放、可擴展和交互式的基於web的門戶（單細胞）OMIC分析
108
Nucleic Acids Res
11.501
BIOMEX: an interactive workflow for (single cell) omics data interpretation and visualization
BIOMEX：用於（單細胞）組學數據解釋和可視化的交互式工作流
109
Nucleic Acids Res
11.501
Combining single-cell RNA-sequencing with a molecular atlas unveils new markers for Caenorhabditis elegans neuron classes
單細胞RNA測序與分子圖譜相結合揭示了秀麗隱杆線蟲神經元類的新標記
110
Nucleic Acids Res
11.501
CReSCENT: CanceR Single Cell ExpressioN Toolkit
CReSCENT:癌症單細胞表達工具包
111
Nucleic Acids Res
11.501
Galaxy HiCExplorer 3: a web server for reproducible Hi-C, capture Hi-C and single-cell Hi-C data analysis, quality control and visualization
Galaxy HicExplorer3：一個用於可複製Hi-C、捕獲Hi-C和單細胞Hi-C數據分析、質量控制和可視化的web伺服器
112
Nucleic Acids Res
11.501
GeneTrail 3: advanced high-throughput enrichment analysis
GeneTrail 3：先進的高通量濃縮分析
113
Nucleic Acids Res
11.501
IRIS3: integrated cell-type-specific regulon inference server from single-cell RNA-Seq
IRIS3：來自單細胞RNA序列的整合細胞類型特異性調控子推理伺服器
114
Nucleic Acids Res
11.501
Matrix factorization and transfer learning uncover regulatory biology across multiple single-cell ATAC-seq data sets
矩陣分解和轉移學習揭示了多個單細胞ATAC-seq數據集的調控生物學
115
Nucleic Acids Res
11.501
OligoMinerApp: a web-server application for the design of genome-scale oligonucleotide in situ hybridization probes through the flexible OligoMiner environment
OligoMinerApp：通過靈活的OligoMiner環境設計基因組級寡核苷酸原位雜交探針的web伺服器應用程式
116
Nucleic Acids Res
11.501
Orthogonal tuning of gene expression noise using CRISPR-Cas
利用CRISPR-Cas正交調諧基因表達噪聲
117
Nucleic Acids Res
11.501
Toward a translationally independent RNA-based synthetic oscillator using deactivated CRISPR-Cas
利用失活的CRISPR-Cas研製一種不依賴平移rna的合成振蕩器
118
Nucleic Acids Res
11.501
Variance-adjusted Mahalanobis (VAM): a fast and accurate method for cell-specific gene set scoring
馬氏方差調整法(VAM):一種快速準確的細胞特異性基因集評分方法
119
Small
11.459
One Cell, One Drop, One Click: Hybrid Microfluidics for Mammalian Single Cell Isolation
單個細胞，單個液滴，單次點擊：用於哺乳動物單細胞分離的混合微流體
120
Small
11.459
Phenome-Genome Profiling of Single Bacterial Cell by Raman-Activated Gravity-Driven Encapsulation and Sequencing
通過拉曼激活重力驅動的封裝和測序的單細胞細菌的現象基因組分析
121
Nano Lett
11.238
Unraveling Cell-Type-Specific Targeted Delivery of Membrane-Camouflaged Nanoparticles with Plasmonic Imaging
闡明帶有等離子體成像的膜偽裝納米顆粒的細胞類型特異性靶向遞送
122
Nano Lett
11.238
Untethered Single Cell Grippers for Active Biopsy
用於主動活檢的無束縛單細胞夾持器
123
Genome Res
11.093
Parallel bimodal single-cell sequencing of transcriptome and chromatin accessibility
轉錄組和染色質可及性的平行雙峰單細胞測序
124
Trends Cancer
11.093
Turning Cold into Hot: Firing up the Tumor Microenvironment
從冷變熱：激發腫瘤微環境
125
J Hematol Oncol
11.059
Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies
靶向嵌合體的蛋白水解（PROTACs）是血液系統惡性腫瘤的新興療法
126
Nat Rev Urol
11
Tracking prostate cancer development at the single-cell level
在單細胞水平上追蹤前列腺癌的發展
127
Genome Biol
10.806
Analysis of endothelial-to-haematopoietic transition at the single cell level identifies cell cycle regulation as a driver of differentiation
在單細胞水平上進行的從內皮細胞到造血細胞的轉化分析確定細胞周期調控是分化的驅動力
128
Genome Biol
10.806
Bayesian model selection reveals biological origins of zero inflation in single-cell transcriptomics
貝葉斯模型的選擇揭示了單細胞轉錄組學中零膨脹的生物學起源
129
Genome Biol
10.806
DISC: a highly scalable and accurate inference of gene expression and structure for single-cell transcriptomes using semi-supervised deep learning
DISC：使用半監督深度學習對單細胞轉錄組進行基因表達和結構的高度可擴展且準確的推斷
130
Genome Biol
10.806
GMM-Demux: sample demultiplexing, multiplet detection, experiment planning, and novel cell-type verification in single cell sequencing
GMM-Demux：單細胞測序中的樣品多路分解、多重檢測、實驗計劃和新型細胞類型驗證
131
Genome Biol
10.806
Quantile normalization of single-cell RNA-seq read counts without unique molecular identifiers
沒有唯一分子標識符的單細胞RNA測序讀數數量的分位數歸一化方法
132
Genome Biol
10.806
Sierra: discovery of differential transcript usage from polyA-captured single-cell RNA-seq data
Sierra：從polyA捕獲的單細胞RNA測序數據中發現差異轉錄本的用法
133
Genome Biol
10.806
Single-cell ATAC-seq signal extraction and enhancement with SCATE
使用SCATE進行單細胞ATAC-seq信號提取和增強
134
Genome Biol
10.806
Single-cell lineage analysis reveals genetic and epigenetic interplay in glioblastoma drug resistance
單細胞譜系分析揭示了膠質母細胞瘤耐藥性的遺傳和表觀遺傳的相互作用
135
Genome Biol
10.806
Single-cell RNA-seq analysis reveals ploidy-dependent and cell-specific transcriptome changes in Arabidopsis female gametophytes
單細胞RNA測序分析揭示擬南芥雌配子體中倍性依賴和細胞特異性轉錄組的變化
136
Biotechnol Adv
10.744
Library preparation for next generation sequencing: A review of automation strategies
下一代測序的文庫準備：自動化策略回顧
137
Cell Death Differ
10.717
Deep profiling of apoptotic pathways with mass cytometry identifies a synergistic drug combination for killing myeloma cells
用質譜分析法對凋亡通路進行的深入分析，確定了一種可殺死骨髓瘤細胞的協同藥物組合
138
Am J Hum Genet
10.502
Human iPSC Modeling Reveals Mutation-Specific Responses to Gene Therapy in a Genotypically Diverse Dominant Maculopathy
人類多能幹細胞建模揭示了在基因型多樣性顯性黃斑病變的基因治療中的突變特異性應答
139
Nat Protoc
10.419
A scalable SCENIC workflow for single-cell gene regulatory network analysis
一種用於單細胞基因調控網絡分析的可拓展SCENIC工作流程
140
Biosens Bioelectron
10.257
Quantifying bacterial spore germination by single-cell impedance cytometry for assessment of host microbiota susceptibility to Clostridioides difficile infection
通過單細胞阻抗細胞術對細菌孢子萌發的定量研究來評價宿主菌群對難感梭菌的敏感性
141
Protein Cell
10.164
Bi-FoRe: an efficient bidirectional knockin strategy to generate pairwise conditional alleles with fluorescent indicators
Bi-FoRe：一種高效的用於產生帶有螢光指示劑成對等位基因的雙向敲入策略
142
Protein Cell
10.164
Single-cell analysis reveals bronchoalveolar epithelial dysfunction in COVID-19 patients
單細胞分析揭示COVID-19患者的支氣管肺泡上皮功能異常
143
Dev Cell
10.092
Actin Polymerization and ESCRT Trigger Recruitment of the Fusogens Syntaxin-2 and EFF-1 to Promote Membrane Repair in C.elegans
秀麗線蟲中融合因子Syntaxin-2和EFF-1的肌動蛋白聚合和ESCRT誘導招募促進膜修復
144
Dev Cell
10.092
Single-Cell Transcriptomic Analyses of the Developing Meninges Reveal Meningeal Fibroblast Diversity and Function
發育中的腦膜的單細胞轉錄組分析揭示腦膜成纖維細胞的多樣性與功能
145
PNAS
9.504
A single-cell Raman-based platform to identify developmental stages of human pluripotent stem cell-derived neurons
基於單細胞拉曼光譜的人類多能幹細胞源性神經元發育階段鑑定平臺
146
PNAS
9.504
Circulating immune cell phenotype dynamics reflect the strength of tumor-immune cell interactions in patients during immunotherapy
循環免疫細胞的表型動態反映了腫瘤-免疫細胞在患者的免疫治療期間相互作用的強度
147
PNAS
9.504
Hedgehog-FGF signaling axis patterns anterior mesoderm during gastrulation
原腸形成過程中Hedgehog-FGF信號軸的前中胚層模式
148
PNAS
9.504
Prototypical pacemaker neurons interact with the resident microbiota
典型起搏神經元與常駐微生物群相互作用
149
PNAS
9.504
Reproductive outcomes predicted by phase imaging with computational specificity of spermatozoon ultrastructure
精子超微結構計算特異性相位成像預測生殖結局
150
PNAS
9.504
Sex differences in neutrophil biology modulate response to type I interferons and immunometabolism
中性粒細胞生物學的性別差異調節對Ⅰ型幹擾素和免疫代謝的反應
151
PNAS
9.504
Single-cell RNA-seq analysis revealed long-lasting adverse effects of tamoxifen on neurogenesis in prenatal and adult brains
單細胞RNA測序分析顯示他莫昔芬對產前和成年大腦神經產生的長期不良影響
152
PNAS
9.504
Stochastic bacterial population dynamics restrict the establishment of antibiotic resistance from single cells
隨機細菌種群動態限制了單細胞對抗生素耐藥性的建立
153
PNAS
9.504
Transcriptome profiling reveals signaling conditions dictating human spermatogonia fate in vitro
轉錄組分析揭示了指示體外人類精原細胞命運的信號條件
154
PNAS
9.504
Wide lag time distributions break a trade-off between reproduction and survival in bacteria
較寬的滯後時間分布打破了細菌繁殖與存活之間的平衡